Showing posts with label danager. Show all posts
Showing posts with label danager. Show all posts

Tuesday, March 31, 2020

What Is a Virus? #Covid19Virus, #CoronaVirustips, #Covid19nz, #lnzlockdown

What Is a Virus?
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A computer illustration of coronavirus particles.
A virus is genetic material contained within an organic particle that invades living cells and uses their host's metabolic processes to produce a new generation of viral particles.


The way they do this varies. Some insert their genetic material into the host's DNA, where it can sit in wait until it's translated at a later date. As the host cell replicates itself, it can make new viruses.

Viruses can also burst their host cell as they expand in numbers, in what's called a lytic cycle of reproduction.

How big are viruses?
The word virus comes from a Latin word describing poisonous liquids. This is because early forms of isolating and imaging microbes couldn't capture such tiny particles.

Virus sizes vary from the extremely minuscule - 17 nanometre wide Porcine Circovirus, for example - to monsters that challenge the very definition of 'virus', such as the 2.3 micrometre Tupanvirus.

Similarly, they come in a range of complexities, containing different proteins or surrounded by an array of shells and envelopes to assist in their infection and reproduction of just about every species across every kingdom of life.

Viruses can be encoded in a variety of ways. Rotaviruses are based on a double strand of RNA, for example. Coronaviruses have a single strand of RNA, which is 'positive sense', as in it can be translated directly into new proteins. Influenza has negative sense RNA, meaning it needs an extra transcribing step before it can make proteins.

Smallpox and herpes viruses are examples of DNA viruses, which force the host to transcribe its genome into RNA on entry.

Sizes of these genomes also vary. Some of the largest can be over a million base pairs long. On the other hand, an RNA virus that infects bacteria, called MS2, has barely 3,500 base pairs.



It's impossible to know with certainty just how many types of viruses exist in the natural world, with numbers climbing as researchers use new tools to search for classified and unknown genetic signatures in the soil, oceans, and even the skies. Rough estimates suggest there could be as many as 100 million types of virus on Earth's surface.



Are viruses alive?
This is a question scientists continue to discuss as definitions of life and ecology change. Current thinking suggests viruses should be considered part of a complex living system, one that extends between all organisms.

'Virions' are the inactive particles that move through the environment, which we don't tend to think of as alive. Only once they're part of a cell do viruses take on living characteristics of their own, borrowing the host's biochemistry to reproduce.

As such, it's more accurate to think of viruses as part of the continuum between chemistry and biology, one that isn't clearly divided



什么是病毒

https://cutt.ly/ltTIqNe 病毒是一种包含在有机颗粒中的遗传物质,该颗粒会侵入活细胞并利用其宿主的代谢过程产生新一代病毒颗粒。
他们执行此操作的方式各不相同。有些人将他们的遗传物质插入宿主的DNA中,可以放置在那里,直到以后翻译。随着宿主细胞自我复制,它可以制造新病毒。
病毒还可以随着其数量的膨胀而破裂其宿主细胞,这就是所谓的繁殖裂解周期。

病毒有多大?
病毒一词来自拉丁语,描述有毒液体。这是因为分离和成像微生物的早期形式无法捕获如此微小的颗粒。
病毒的大小从极小的微粒(例如17纳米宽的猪圆环病毒)到挑战“病毒”定义的怪物,例如2.3微米的Tupanvirus。into living and non-living.

同样,它们具有一系列复杂性,包含不同的蛋白质,或者被一系列的壳和包膜包围,以帮助它们感染和繁殖每个生命王国中的几乎每个物种。

病毒可以通过多种方式进行编码。轮状病毒例如基于RNA的双链。冠状病毒具有单链RNA,具有“正向意义”,因为它可以直接翻译成新蛋白质。流感具有负义RNA,这意味着它需要额外的转录步骤才能制造蛋白质。

天花和疱疹病毒就是DNA病毒的例子,它们迫使宿主在进入时将其基因组转录成RNA。

这些基因组的大小也不同。最大的一些可能超过一百万个碱基对。另一方面,一种感染细菌的RNA病毒,称为MS2,仅有3500个碱基对。

无法确定自然世界中存在多少种病毒,随着研究人员使用新工具在土壤,海洋甚至天空中寻找机密和未知的遗传特征,数字正在攀升。粗略估计表明,地球表面上可能有多达1亿种病毒。

病毒还活着吗?
随着生命和生态变化的定义,这是科学家继续讨论的问题。当前的想法表明,应将病毒视为复杂的生命系统的一部分,该系统在所有生物之间传播。
“病毒粒子”是在环境中移动的惰性粒子,我们通常不认为它们是活的。病毒一旦进入细胞,它们便会发挥自身的生存特征,借用宿主的生物化学进行繁殖。
因此,将病毒视为化学和生物学之间连续体的一部分是更准确的,这没有明确划分






Friday, December 23, 2011

Superlight and Supersharp folding knife -- credit card size!

CARDSHARP 2 | CREDIT CARD FOLDING KNIFE | Image 
Sometime ago we did a post on the amazing CardSharp by Iain Sinclair. Well, Iain Sinclair Design wanted us to check out the new improved version of the superlight and supersharp utility knife, the CardSharp2. The James Bond style credit card sized pocket knife has some new and updated features, it has a stiffer, polypropylene body (living hinges guaranteed for life), and a unique safety lock (cannot open in pocket or drawer and child proof). 
With just three ingenious origami style folding operations, metamorphosise the card into an elegant pocket utility tool. Slimmer and lighter than an ordinary knife, it´s extra long stainless steel surgical blade ensures longer lasting rust free sharpness. The superlight polypropylene body includes a built-in protective sheath that helps prevent injury or blunting. CardSharp2 is an ingenious conversation piece. A sharp idea that slips safely inside your wallet or kit bag.
Suitable for camping and expedition use, Cardsharp is an essential outdoor companion/survival tool. The waterproof design is dishwasher proof and will not rust up like conventional penknives - uniquely friction free as there are no conventional hinges. 
We must say, we tested this thing on a variety of materials, and man...it is sharp! This is a must have for gadget lovers, just pack the 13-gram bladed perfection into your wallet and you e ready to go!
LIGHTWEIGHT - 13 grams (regular Stanley® type utility knife weighs around 150 grams, Leatherman® same sized blade knife weighs around 85 grams, smallest Victorinox® Swiss Army penknife weighs around 23 grams).
ULTRA THIN - 2.2 mm thick (traditional Stanley® utility knife body thickness is around 25 mm).
RAZOR SHARP - Surgical blade technology with extra long 65mm cutting edge ensures longer lasting sharpness (Stanley® utility knife blade edge is only 25mm long). Blade made from high quality rust free stainless steel. Independent testing laboratory; CATRA awarded Cardsharp penknife; VERY GOOD status for sharpness (ICP mm) and life (TCC mm). Blade color choice: Teflon Black or Natural Brushed Stainless Steel.
SAFETY - Blade edge is protected when stored in wallet, drawer, or kit bag which avoids accidents and blunting (blunting often caused by rubbing against other knives or tools). Integral blade sheath cannot be lost. Protective hilt appears when opened. When docked in closed position, design prevents injury. Cannot fold accidentally (as some folding pocket knives). Blade is locked solidly in open, cutting mode with no blade tremor allowing accurate precision cutting.
WATERPROOF - Machine washable with no hinged parts to rust up like ordinary folding pocket knives.
ECO FRIENDLY - Lightness and flatness reduces storage and shipping costs including carbon footprint. Simple two part construction with automated assembly saves manufacturing waste.
PERMUTABILITY - Highly suitable for customization by pad printing or invisible label (printed 1-4 color lithographic) and/or custom laser engraving blade - please email us if you have a promotion inquiry).
PACKAGING - Various options available including slimline card eco-pack for gift/mail order and harder sell retail design with euro hook
LEGAL - Blade is under 3” (76 mm) and is visible when closed so easily identifiable as a knife (optional clear body versions show blade from both sides - P.O.A). Note: legal restrictions vary internationally.
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